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The Immune System – Your First Line of Disease Defense
Excerpt from “Beta Glucan
– Immunition to Win Your Body War” The immune response is our body’s incredibly complex defense system comprised of trillions of cells with the purpose to defend us against substances that do not belong in our bodies and can potentially cause us harm. Immunologist segregate the immune response into that involving a humoral system comprised primarily of B-cells which produce antibodies, and the cell mediated system containing macrophages and the various T-Cells. Microparticulate Beta glucan works through activation of unique receptors on the surface of the Macrophage and Dendritic immune cells that are exact matches for the Beta glucan molecule. This means Beta 1,3/1,6 glucan extracted from yeast cell wall stands alone in ability to powerfully potentiate these huge white immune blood cells, which are the first line of defense in your body. Macrophage literally means, “big eater” and these constantly vigilant policeman in your system are just that! These immune cells recognize, engulf and destroy any cells, organisms or substances that are “non-self” or do not belong in the body. Macrophages are the immune cells that start and play a major roll in directing the immune process. They not only fight individually, but they send chemical faxes to the other defense fighters in the immune system. The key is to enhance their arsenal of defense by arming them with better weapons and making their ability to recognize the “bad guys” more readily than normal or when suppressed. The immune response is activated when ill health invaders such as viruses, bacteria, fungi and parasites enter our body through the air we breathe, the water we drink and the food we eat; plus our skin. The white blood cells called macrophages, engage these various invaders and literally eat them without regard to the type of invader. This response is known as “nonspecific” with the only criteria being the macrophage knows what is being attacked does not originate from the host body and is “nonself.” The macrophages are critical in alerting the remainder of the immune response, including the Helper T-Cells that in turn communicate with the cytotoxic killer T-Cells, the NK (natural killer) T-Cells and the B-Cells to initiate and fulfill the immune cascade. The macrophages produce cytokines that are essentially the protein messengers of the immune system. Beta glucan is again unique in promoting the Interleukin 1 (IL1) production that is critical to insulin production in the pancreas. The Beta glucan nutritionally modulates and potentiates the macrophage to maintain a state of readiness. The activated macrophage digest an invader such as a virus and displays pieces of the virus known as antigens on the macrophage surface. All “nonself” has unique antigens that act as name tags for the millions of viruses, bacteria, fungi and parasites that attack us daily. The helper T-Cells recognize specific antigens on the macrophage surface (apc cells) and binds to the macrophage. The helper T-Cell then evaluates the situation and calls in the various immune system components needed to fight back effectively against a specific antigen. The helper T-Cells also activate the humoral side of the immune response, including the B-Cells which on presentation of a specific antigen, produce specific antibodies for killing or neutralizing the invader. These antibodies then bind to the antigens on the surface of the health invaders, enabling the macrophages and various T-Cells to attack to kill the invaders by ingestion or by emission of various chemicals. This binding also alerts blood components known as complements (actually 25 different proteins) to puncture holes in invader infected cells. This facilitates phagocytosis, a big word meaning the eating by phagocytes such as the macrophage of the invader. As the health invader is brought under control, the activated T and B-Cells are signaled to stop attacking by suppressor T-Cells. Another type of T-Cell, the Memory T-Cells, remain behind to respond quickly against the same type of invader, if the same health invader attempts to attack again. We often translate this to mean we are building up an immunity to various viruses, bacteria, funguses or parasites. In various parts of the body, the macrophage may be referred to as: Lungs - Alveolar cells; Kidneys - Mesangial cells; Brain - Microglial cells; Liver - Kupffer cells; and Skin – dendritic Langerhans cells. The macrophages, as each of us, become less able to fight back and their vision becomes suspect as we grow older or are compromised by disease. Beta glucan helps overcome these deficiencies by arming the macrophages with “immunition™” to have greater fire power and improved ability to recognize the pathogens that assault our bodies daily in the form of viruses, bacteria, fungi, parasites and radiation. Proper diet, adequate rest, moderate exercise, reduced stress and appropriate supplementation with vitamins, minerals, enzymes and supplements such as microparticulate beta glucan are essential to maintain or bring back an immune response to peak condition to both recognize and destroy the pathogens that otherwise will destroy us. That "superior immune potentiation" Beta glucan, based on published peer-reviewed U.S. Medical School research, is MG Glucan available exclusively in the NSC-24 Immunition Products, processed in accord with U.S. Patent 6,476,003. Listen Daily to Live Health Talk on National Radio on "Healthy, Wealthy and Wise" hosted by Frank M. Jordan.
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