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Allergies, the Immune System and Beta Glucan
What
is an Allergy and How Do I Become Allergic? Allergies are a collection of disease symptoms caused by an overaggressive immune response mistakenly identifying harmless substances and attacking them as if they were dangerous health invaders to our bodies. A hyper immune response causing allergic reactions such as hay fever, asthma and skin rashes is in need of the ability to recognize and distinguish between harmless allergens (dust, food, pollen, etc.) and dangerous pathogens (viruses, bacteria, parasites and fungi). Allergies are suffered by millions of people and come into our bodies by exposure of: (1) skin to chemicals and toxins; (2) the respiratory system to particles of dust or pollen or (3) the stomach and intestines to a particular food or food related substance. The unique factor in allergies is the majority of people do not respond to the symptoms that create havoc in the health of those with allergic reactions. The reason some have allergies and some do not? The exact answer is not known and allergies are recognized to be hereditary in some cases. What we do know for certain is an immune system operating normally at peak condition operates an arsenal of defense against pathogens such as bacteria, viruses, parasites and fungi that invade our bodies every second of every day. Certain white immune cells called phagocytes, (macrophages and T cells - leukocytes) when at peak condition are able to engulf, disable and dispose of the antigens, or unique protein identifiers, present on every microorganism, including allergens that cause allergies. These are the "Pac Men" of your immune system that act as vacuum cleaners and disposals for the millions of "things" that enter your body constantly that did not originate in the body i.e. non-self. As with many of us, the immune system can have impaired vision; often unable to clearly distinguish the good guys from the bad guys. As we age, this non-recognition becomes more prevalent. If the alarm is sounded to attack a good guy mistakenly identified as a bad guy, you have an allergic reaction such as runny nose, tearing eyes, irritated skin or labored breathing. Different immune systems become suppressed or deficient to different "good guys" for reasons not yet known and thus some people are allergic to pollen; some to strawberries and others to certain cosmetics; while their friends can stand in a ragweed fog, eating strawberries while putting on makeup with no reaction whatsoever! The best way to conquer allergies is to never get allergies. A sound logic, but how is it possible? The key is to boost your immune response to enable better recognition of what is truly harmful versus that which is not, as these microorganisms enter your body through your skin, lungs or stomach/intestines. Science has demonstrated micronized Beta 1,3/1,6 glucan, available commercially as NSC-24 and NSC-100 Immunition(tm) products, potentiates your immune response to provide better recognition and then sounds the false alarm alert to bring the fire trucks of the immune system home where there is only smoke and no fire. But let's learn more about what allergies actually are and how the immune response does respond to these false alarms.
The Allergic Response The macrophages then sound the alarm and send out chemical protein faxes (cytokines) to the Helper T cells and the B cells to produce ammunition to fight back and destroy the allergens thought to be health threats. The ammunition produced by the immune system comes as specific health bullets known as antibodies. Antibodies are produced for real pathogens such as bacteria and viruses, but for allergies the antibody specifically is an immunoglobulin known as IgE. These IgE antibodies then are circulated in your body and attach to cells in your tissues called mast cells (basophils) which contain granules of histamines. When a specific allergen, which may be ragweed pollen, a food or other agent, comes in contact with the body again, the allergens attach to the mast cells with the antibody and histamine is released into the body. This production of histamines to attack a harmless agent thought to be dangerous is an inappropriate reaction by the immune system known as hypersensitivity. The histamine attack causes what we then experience and call allergy symptoms, which vary according to the allergy. Histamines cause blood vessels to widen, fluids to leak into tissues, and muscles to go into spasms. Symptoms may be restricted to the skin as a rash or itching that may swell. In the upper airways there will be inflammation or mucus secretion, sneezing in hay fever and spasms accompanied by narrowing of the airways in asthma. The eyes will show inflammation with redness and tearing, while in the stomach we can experience vomiting and diarrhea. Anyone who has experienced these symptoms knows allergies are a serious condition that can render a person disabled physically until brought under control. The most common allergies are hay fever (rhinitis) and asthma, endured by 37+ million people. During the spring and summer particularly, ragweed fills the air with microscopic particles that enter the body and trigger the sneezing, runny nose, tearing eyes and overall misery of hay fever. In advanced stages, asthma occurs, with attendant breathing difficulties, weakness and spasms of the chest that can be life threatening in advanced stages. The most common causes of Type I Hypersensitivity reactions are flowers, grasses, tree pollens, animal dander, house dust, yeast and certain drugs and food, in addition to bee and wasp venom. Of the food allergens, the most common are milk, eggs, shellfish, dried fruits, nuts and certain food dyes. In addition to hay fever and asthma, Type I reactions also include hives (urticaria), angioedema, and anaphylactic shock. Anaphylactic shock is a rare, severe and life-threatening allergic reaction. The reaction is normally to an insect sting or as a reaction to an injected drug - for example, penicillin. Less commonly, the reaction occurs after a particular food is taken by mouth. Massive amounts of histamine are released and a sudden severe lowering of blood pressure occurs. Medical help should be summoned immediately and those diagnosed, according to the AMA, should always have a preloaded syringe of "epinephrine" that is often lifesaving. Type IV Hypersensitivity reactions are responsible for contact dermatitis which is a rash caused by contact with substances such as elastic, cosmetics or detergents.
Food Allergies This expansion in turn allows large undigested food particles to pass through and into the body to the tissues and potentially the blood stream. These particles then settle in different parts of the body resulting in skin allergies and possibly a host of other diseases, including chronic fatigue syndrome, epilepsy and attention deficit disorder. Food is at this point harming the body instead of providing nourishment.
What to Do to Avoid or Calm Allergies If the immune system does not improperly respond because the allergen is recognized as harmless, there is no allergic reaction. If the immune system is already hyper in the midst of an allergic response, the Beta glucan in NSC-24 and NSC-100 Immunition(tm) will modulate, or calm down the immune response and return the immune system to normal to alleviate the allergy symptoms. The second most effective method in treating allergies is to avoid contact with the allergen causing the allergic reaction. This is not difficult with foods, but can be very difficult with pollen and environmental allergies. Filters, special mattresses and air conditioning all help in this regard. Anti-histamines and corticosteroids are common over-the-counter agents or drugs used to alleviate allergy symptoms. While often effective with calming effects and providing much needed rest, a much better solution is the Beta glucan which enables your immune system to stop the allergic response before happening instead of responding afterward. Immunotherapy to build up antibodies is also effective in which allergens are injected slowly over time to build up antibodies to the allergic reaction. This treatment is often successful, but can take months or years and is generally expensive. Certain supplements, herbs and vitamins can also provide help in fighting allergies nutritionally and naturally, including:
Diet is also a major player in both creating and resolving allergies. Avoid sugar, refined carbohydrates and caffeine. Don't eat the same foods every day if you are having allergic reactions, but vary your diet daily with a minimum four day rotation. Other ways to fight back are to add plants and a good filtration system to your home and office area. Take supplements, nutrients and herbs that strengthen the immune system, particularly micronized Beta glucan in NSC-24 and NSC-100 Immunition(tm) products. Avoid both emotional and physical stress to the extent possible. Both are known to trigger and aggravate allergic reactions. Get adequate rest with moderate exercise. Allow 10 to 45 days for signs of alleviation. If your allergies persist or you have severe reactions, seek professional medical advice, as you may have a pathogen that is not an allergic reaction causing your personal problem. Your immune system is the key to not only resolution and avoidance of allergic reactions, but to fighting back and conquering the preponderance of pathogens that assault our bodies daily as ill-health invaders. With an immune system at or returned to peak condition, you can enjoy both a quality and quantity of life manifested by longevity in good health.
About the Author
© Reprinted Permission of Macrophage Technologies, Inc. (MTI)
Copyright © 1998 by Nutritional Supply Corporation.
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